化学化工学院
杨建梅
分析化学专业，副教授，博士，硕士生导师
云南省“兴滇英才支持计划”青年人才
联系方式：yangatynnu@163.com
主要研究方向
纳米材料及生物传感器
主要招生专业
分析化学 化学与生物传感
教育与工作经历:
2011年9月～2015年6月，云南师范大学 化学化工学院 化学，学士
2015年9月～2020年6月，西南大学 化学化工学院 分析化学 博士
获奖成果和荣誉称号：
杨建梅. 云南省“兴滇英才支持计划”——青年人才专项，2022年
主持科研项目
1.国家自然科学基金项目，高效协同抗污传感界面的构建及血清中心梗microRNA的便捷高灵敏电化学检测研究，执行时间：2024/01-2027/12
2.云南省基础研究计划项目（面上项目），高灵敏、高稳定性microRNA电化学生物传感器的构建研究，执行时间：2023/06-2026/05
3.云南省基础研究计划项目（青年项目），光刺激可再生防污癌症标志物电化学生物传感器的研制及应用，执行时间：2022/06-2025/05
4.云南省教育厅科学基金项目，血糖仪用于癌症标志物的即时检测，执行时间：2021/03-2022/02。
代表性著作、论文、专利等
1.Jian-Mei Yang, Xiao-Long Li, Bing-Ying Jiang*, Ruo Yuan, Yun Xiang*. In situ-generated multivalent aptamer network for efficient capture and sensitive electrochemical detection of circulating tumor cells in whole blood. Analytical Chemistry, 2020, 92(11), 7893-7899.
2.Jian-Mei Yang, Bao-Ting Dou, Ruo Yuan, Yun Xiang*. Proximity binding and metal ion-dependent DNAzyme cyclic amplification-integrated aptasensor for label-free and sensitive electrochemical detection of thrombin. Analytical Chemistry, 2016, 88(16), 8218-8223.
3.Jian-Mei Yang, Bao-Ting Dou, Ruo Yuan, Yun Xiang*. Aptamer/protein proximity binding-triggered molecular machine for amplified electrochemical sensing of thrombin. Analytical Chemistry, 2017, 89(9), 5138-5143.
4.Jian-Mei Yang, Yun-Lan Wu, Chun-Fang Gan*, Ruo Yuan, Yun Xiang*. Target-programmed and autonomous proximity binding aptasensor for amplified electronic detection of thrombin. Biosensors and Bioelectronics, 2018, 117, 743-747.
5.Jian-Mei Yang, Xiao-Tong Huang, Chun-Fang Gan*, Ruo Yuan, Yun Xiang*. Highly specific and sensitive point-of-care detection of rare circulating tumor cells in whole blood via a dual recognition strategy. Biosensors and Bioelectronics, 2019, 143, 111604.
6.Jian-Mei Yang*, Qian Bi, Xin-Mei Song, Ruo Yuan, Yun Xiang*. Aptamer/organometallic receptor-based and label-free sensitive electrochemical detection of amino acid via multi-pedal DNA walker/DNAzyme amplifications. Sensors & Actuators: B. Chemical, 2023, 375, 132876.
7.Jian-Mei Yang*, Xiao-Yan Gan, Xin-Mei Song, Ruo Yuan, Yun Xiang*. Apamer-based sensitive and label-free electrochemical detection of neutrophil gelatinase-associated lipocalin via recycling amplification cascades. Analytica Chimica Acta, 2022, 1233, 340515.
8.Lingl-Li Wang, Teng-Teng Shan, Lu Pu, Jin Zhang, Rong Hu, Yun-Hui Yang, Jian-Mei Yang*, Yan Zhao*. Glucometer-based electrochemical biosensor for determination of microRNA (let-7a) using magnetic-assisted extraction and supersandwich signal amplifcation. Microchimica Acta, 2022, 189, 444.
9.Yu-Long Li, Fa-Ting Xie, Cao Yao, Gui-Qun Zhang, Yan Guan, Yun-Hui Yang, Jian-Mei Yang*, Rong Hu*. A DNA tetrahedral nanomaterial-based dual-signal ratiometric electrochemical aptasensor for the detection of ochratoxin A in corn kernel samples. Analyst, 2022, 147, 4578-4586.
10.Ling-Li Wang, Hui-Wen Yang, Fang-Dao Zhu, Shao-Ming Chi, Jin Zhang, Jian-Mei Yang*, Yan Zhao*, Host-guest inclusion systems of two bioactive natural products derivantives and three polyamine-modified β-cyclodextrins: Preparation, characterization, biological activity. Journal of Drug Delivery Science and Technology, 2022, 67, 102940.
11.Tengteng Shan, Lingrong Cui, Huimin Zhang, Kaiqin Li, Jianmei Yang*, Yan Zhao*, Yun Xiang, Ruo Yuan. Target-promoted activation of DNAzyme walker for in situ assembly of hemin/G-quadruplex nanowires enable ultrasensitive and label-free electrochemical myocardial microRNA assay. Talanta, 2025, 281:126923.
12.Yihe Li, Lingrong Cui, Zhijiang Dai, Jin Zhang, Jianmei Yang*, Yan Zhao*, Yun Xiang, Ruo Yuan. Coupling an anti-fouling recognition interface with dual biological signal amplifications for ultrasensitive and label-free electrochemical myocardial microRNA assay in complex sample matrix. Microchemical Journal, 2025, 218, 115544.
13.Jianmei Yang*, Qianhong Chen, Ruo Yuan, Yun Xiang*. Highly catalytic FeS2@CoS2 core/shell nanocubes for ultrasensitive electrochemical assay of microphthalmia-associated transcription factor via nucleic acid signal amplification cascades. Analytical Chemistry, 2025, 97, 50, 27716-27723.
14.Linru Bai, Benqi Chen, Yan Xu, Mingjia Liu, Yunhui Yang*, Jianmei Yang*, Rong Hu*. A multi‑thionine DNA network‑driven electrochemical aptasensor with dual signal amplification for ultrasensitive interleukin‑6 detection. Microchim Acta, 2025, 192, 661.
15.Lingli Wang, Tong Yang, Long Huang, Jin Zhang, Rong Hu, Yunhui Yang, Jianmei Yang*, Yan Zhao*. Highly sensitive biosensor for visual detection of Hg2+ based on dual signal amplification strategy. Chinese Journal of Analytical Chemistry, 2024, 52, 1678-1686.
16.Zhijiang Dai, Tengteng Shan, Yihe Li, Jianmei Yang*, Yan Zhao*. Regenerable electrochemical biosensor based on multi-legged DNA walker and host-guest chemistry for highly sensitive detection of myocardial infarction-related microRNA. Chemical Journal of Chinese Universities, 2026, 47, 20250255.
主讲课程
本科生课程《分析化学》、《分析化学实验》、《仪器分析》、《仪器分析实验》、《环境化学》