化学化工学院
张俊峰
有机化学专业，教授，博士生 导师
联系方式：junfengzhang78@126.com; 59971947@qq.com
学术任职及兼职
1. 中国感光学会-光学传感与诊疗专业委员会学术委员会委员
2. 《Chinese Chemical Letters》（中国化学快报）编委
主要研究方向
近红外荧光探针；光学传感与肿瘤诊疗；功能性荧光染料设计与应用
主要招生专业
有机化学；分析化学；光学工程
教育与工作经历:
1997年09月～2001年07月，河南师范大学化学与环境科学学院，化学教育，理学学士
2001年09月～2004年07月，云南师范大学化学化工学院，物理化学，理学硕士
2004年09月～2007年07月，中国科学院理化技术研究所，有机化学，理学博士
2007年09月～2008年07月，云南师范大学化学化工学院，药物化学系，讲师
2008年07月～2009年07月，云南师范大学化学化工学院，药物化学系，副教授
2009年07月～2011年06月，韩国 Korea University，基础科学系，博士后（研究教授）
2011年06月～2015年09月，云南师范大学化学化工学院，药物化学系，副教授
2015年10月～至今，云南师范大学化学化工学院，有机化学系，教授
获奖成果和荣誉称号：
1. 张俊峰，吴相华，刘波，高选择性识别生物小分子荧光/电化学传感器构建及其机制研究
，云南省科学技术奖 (自然科学类) 三等奖，2020年；
2.张俊峰，云南师范大学“优秀青年学者”，2013年
3.张俊峰，云南师范大学“联大青年学者”，2018年；
4.张俊峰. 云南省“兴滇英才支持计划”青年拔尖人才，2019年；
5.张俊峰，云南省中青年学术技术带头人，2019年；
6.张俊峰，“全国科技成果评价专家库”专家，2021年；
7.张俊峰，云南师范大学“联大学者”，2023年；
主持科研项目
1. 国家自然科学基金项目（地区基金项目），基于新型半花菁荧光团的小分子近红外II区荧光传感体系构建及癌细胞靶向示踪与光治疗，执行时间：2024/01-2027/12；
2.云南省教育厅光功能材料科技创新团队，执行时间：2023/01-2025/12；
3.云南师范大学传感、分离与催化功能材料“联大”优秀科研创新团队，执行时间：2022/10 -2025/09；
4.国家自然科学基金项目（地区基金项目），检测关联性生物活性物种的双位点协同响应荧光探针设计、合成及荧光成像研究，执行时间：2021/01-2024/12；
5.国家自然科学基金项目（地区基金项目），新型近红外诊疗一体荧光探针的设计、合成和生物学应用研究，执行时间：2019/01-2022/12；
6.国家自然科学基金项目（青年基金项目），类氟硼吡咯检测硫醇的荧光探针设计、合成及应用研究，执行时间：2014/01-2016/12；
7.国家自然科学基金项目（地区基金项目），基于1,8-萘酰亚胺金属配合物的阴离子荧光探针及其生物学应用研究，执行时间：2013/01-2016/12；
代表性著作、论文、专利等
1.Junfeng Zhang, Lingyu Jin, Bin Xiao, Dongeun Kim, Siwei Hua, Yangmei Hua, Yangjie Liu, Xuefei Huang, Junfeng Kou*, Bo Liu, Xianghua Wu, Xiaolin Zhong, Amit Sharma, Yuda Zhu*, Wen Xiu Ren*, and Jong Seung Kim* NIR-Responsive Xanthene Probes for Dual-Mode Cancer Treatment and Bioimaging. Anal. Chem., 2025, 97(36), 19597-19605.
2.Mingrui Zhang, Lingyu Jin, Yuda Zhu, Junfeng Kou, Bo Liu, Jing Chen, Xiaolin Zhong, Xianghua Wu*, Junfeng Zhang*, Wenxiu Ren* A near-infrared II fluorescent dye based on oxanthracene: Real-time imaging of drug-induced acute liver injury and photothermal therapy for tumor. Chinese Chemical Letters, 2025, 36(10), 110772.
3.Qiao Zhao, Fengying Yuan, Bin Xiao, Yanyan Zeng, Junfeng Kou,* Bo Liu, Xiaoqing Mou, Xianghua Wu, June Seok Heo, Xiaolin Zhong, Junfeng Zhang,* and Wen Xiu Ren* A lysosome-targeted dual-responsive fluorescent probe for simultaneous detection of NO and H2S in living cells, wild-type C. elegans and zebrafish. Dyes and Pigments, 2024, 228, 112224.
4.Fengying Yuan, Qiao Zhao, Yanyan Zeng, Xu Fang Liao, Jiali Li, Bo Liu, Jun Feng Kou, Xiaolin Zhong, Xiang Hua Wu,* Jun Feng Zhang*, Wen Xiu Ren* A COX2-targeting cancer-specific fluorescent probe for hydrogen sulfide detection in living cells, Caenorhabditis elegans, and zebrafish. Analyst, 2024, 149(5), 1489-1495.
5.Yu Min Wang, Jiali Li, Jian Hua Chen, Bo Liu, Yanyan Zeng, Ja-Yun Lim, Ya Ting Liu, Jun Feng Zhang*, Xiang Hua Wu*, and Wen Xiu Ren* A dual-responsive fluorescent probe for detection of H2O2 and HClO in living cells and Caenorhabditis elegans. Dyes and Pigments, 2023, 215, 111218.
6.Arup Tarai, Yuan Li, Bo Liu, Dan Zhang, Jia Li, Wei Yan, Junfeng Zhang,* Junle Qu,* Zhigang Yang,* “A review on recognition of tri-/tetra-analyte by using simple organic colorimetric and fluorometric probes” Coordin. Chem. Rev. 2021, 445, 214070.
7.Yu-Qiang Zhao, Jiahong Duan, Le Yu, Ilwha Kim, Yumin Wang, Yi-Cheng Ma, Cheng-Gang Zou, Ying Zhou,* Jun Feng Zhang*, Jong Seung Kim*, “Metabolic iron detection through divalent metal transporter 1 and ferroportin mediated cocktail fluorogenic probes” Chem. Commun., 2021, 57, 7902-7905.
8.Xianghua Wu, Yuxun Lu, Bo Liu, Yu Chen, Junfeng Zhang*, Ying Zhou* “A H2S-triggered two-photon ratiometric fluorescent theranostic prodrug for bio-imaging” Chinese Chemical Letters, 2021, 32, 2380-2384.
9.Le Yu, Jun Feng Zhang, Mingle Li, Dewei Jiang, Ying Zhou,* Peter Verwilst* Jong Seung Kim*, “Combining viscosity-restricted intramolecular motion and mitochondrial targeting leads to selective tumor visualization”, Chem. Commun., 2020, 56, 6684-6687.
10.Lina Huang, Yu Chen, Yuqiang Zhao, Yumin Wang, Junwei Xiong, Junfeng Zhang,* Xianghua Wu,* Ying Zhou,* “A ratiometric near-infrared naphthalimide-based fluorescent probe with high sensitivity for detecting Fe2+ in vivo” Chinese Chemical Letters, 2020, 31, 2941-2944.
11.Keying Bi, Rui Tan, Ruiting Hao, Lanxi Miao, Yanqi He, Xianghua Wu, Junfeng Zhang*, Rui Xu*, “A carbazole-hemicyanine dye based ratiometric fluorescent probe for selective detection of bisulfite (HSO3 -) in cells and C. elegans” Chinese Chemical Letters, 2019, 30, 545-548.
12.Xue-Mei Li, Rui-Rui Zhao, Yan Yang, Xue Wei Lv, Yu-Ling Wei, Rui Tan, Jun-Feng Zhang*, Ying Zhou*, “A Rhodamine-based fluorescent sensor for chromium ions and its application in bioimaging” Chinese Chemical Letters, 2017, 28, 1258-1261.
13.Huan Wang, Dan Yang, Rui Tana, Zhang Jian Zhoua, Rui Xu, Jun Feng Zhang*, Ying Zhou*， “A cyanine-based colorimetric and fluorescence probe for detection of hydrogen sulfide in vivo” Sensors and Actuators B: Chemical, 2017, 247, 883-888.
14.Junchao Xu, Jian Pan, Xiaoming Jiang, Caiqin Qin, Lintao Zeng*, Huan Zhang, Jun Feng Zhang* “A mitochondria-targeted ratiometric fluorescent probe for rapid, sensitive and specific detection of biological SO2 derivatives in living cells” Biosensors and Bioelectronics, 2016, 77, 725-732.
15.Xue-Mei Li, Rui-Rui Zhao, Yu-Ling Wei, Dan Yang, Zhang-Jian Zhou, Jun-Feng Zhang*, Ying Zhou “A rhodamine derivative for Hg2+-selective colorimetric and fluorescent sensing and its application to in vivo imaging” Chinese Chemical Letters, 2016, 27, 813-816.
16.Lin E. Guo, Jun Feng Zhang, Xin Yi Liu, Li Mei Zhang, Hong Li Zhang, Jian Hua Chen, Xiao Guang Xie, Ying Zhou, Kaijun Luo, Juyoung Yoon “ A Phosphate Ion Targeted Colorimetric and Fluorescent Probe and Its Use to Monitor Endogeneous Phosphate Ion in a Hemichannel- Closed Cell” Anal. Chem., 2015, 87, 1196-1201.
17.Jun Feng Zhang,* Lin E Guo, Tie Nan Zang, Yu Lian Duan, Xin Yi Liu, Zhigang Yang, Peter Verwilst, Kaijun Luo, Guang Ke Wang, Jun Feng Kou, Ying Zhou*, Jong Seung Kim* “Highly Selective In Vivo Imaging of Endogenous/Exogenous Phosphate Ion over ATP and PPi” Chem. Asian J., 2015, 10, 1165-1169.
18.Lin E. Guo, Xin Yi Liu, Huan Wang, Qiu Ling Chen, Guang Ke Wang, Kaijun Luo, Qi Li Mi, Ying Zhou,* Jun Feng Zhang* “Iron(III)-Selective Chelation-Enhanced Fluorescence Sensing for In Vivo Imaging Applications” Chem. Asian J., 2015, 10, 1898-1902.
19.Ying Zhou, Jun Feng Zhang, Juyoung Yoon*“Fluorescence and Colorimetric Chemosensors for the Fluoride Ion Detection” Chem. Rev., 2014, 114, 5511-5571.
20.Xiao Ju Zou, Yi Cheng, Lin E. Guo, Wen Xiang Liu, Mei Juan Liu, Cheng Gang Zou, Ying Zhou*, Jun Feng Zhang* “A lysosome-targeted fluorescent chemodosimeter for monitoring endogenous and exogenous hydrogen sulfide by in vivo imaging” Chem. Commun., 2014, 50, 13833-13836.
21.Guang Ke Wang, Qi Li Mi, Li Yun Zhao, Jun Jie Hu, Lin E Guo, Xiao Ju Zou, Bo Liu, Xiao Guang Xie, Jun Feng Zhang*, Qi Hua Zhao, Ying Zhou* “A Pyrene Derivative for Hg2+- Selective Fluorescent Sensing and Its Application in In Vivo Imaging” Chem. Asian J., 2014, 9, 744-748.
22.Dong Xiang Li, Jun Feng Zhang, Yoon Hee Jang, Yu Jin Jang, Dong Ha Kim, Jong Seung Kim*,“Plasmonic-Coupling-Based Sensing by the Assembly and Disassembly of Dipycolylamine- Tagged Gold Nanoparticles Induced by Complexing with Cations and Anions” Small, 2012. 8(9), 1442-1448.
23.Jun Feng Zhang, Ying Zhou, Juyoung Yoon*, Jong Seung Kim*, “Recent Progress on Fluorescent and Colorimetric Chemosensors for Detection of Precious Metal Ions (Silver, Gold and Platinum ions)” Chem. Soc. Rev. 2011. 40, 3416-3429.
24.Jun Feng Zhang, Sooyeon Kim, Ji Hae Han, Seung-Jea Lee, Tuhin Pradhan, Qian Yong Cao, Suk Joong Lee, Chulhun Kang, Jong Seung Kim*, “Pyrophosphate-Selective Fluorescent Chemosensor Based on 1, 8-Naphthalimide-DPA-Zn(II) Complex and Its Application for Cell Imaging” Org. Lett.. 2011, 13, 5294-5297.
25.Jun Feng Zhang, Chang Su Lim, Sankarprasad Bhuniya, Bong Rae Cho, Jong Seung Kim*, “A Highly Selective Colorimetric and Ratiometric Two-Photon Fluorescent Probe for Fluoride Ion Detection” Org. Lett., 2011, 13, 1190-1193.
26.Jun Feng Zhang, Minsung Park, Wen Xiu Ren, Youngmee Kim, Sung Jin Kim, Jong Hwa Jung, Jong Seung Kim*, “A pellet-type optical nanomaterial of silica-based naphthalimide– DPA–Cu(II) complexes: recyclable fluorescence detection of pyrophosphate” Chem. Commun., 2011, 47, 3568-3570.
27.Jun Feng Zhang, Ying Zhou, Juyoung Yoon, Youngmee Kim, Sung Jin Kim, Jong Seung Kim*, “Naphthalimide Modified Rhodamine Derivative: Ratiometric and Selective Fluorescent Sensor for Cu2+ Based on Two Different Approaches” Org. Lett., 2010, 12, 3852-3855.
28.Jun Feng Zhang, Chang Su Lim, Bong Rae Cho, Jong Seung Kim*, “A two-photon excited luminescence of water-soluble rhodamine-platinum(II) complex: Fluorescent probe specific for Hg2+ detection in live cell” Talanta, 2010, 83(2), 658-662.
1.吴相华，张俊峰，刘波，王玉敏，专利名称：一种荧光探针分子及其制备方法与应用，发明专利，专利授权号：ZL202110566718.7，专利授权日期：2022/06
2.吴相华，张俊峰，寇军锋，刘波，肖彬，一种苯并吡喃鎓荧光染料分子、制备方法及应用，发明专利，专利授权号：ZL202411311928.1
3.寇军锋，刘波，吴相华，张俊峰，王春梅，一种D-π-A型半花菁染料、制备方法及应用，专利号：ZL202411307238.9
4.刘波，寇军锋，张俊峰，吴相华，王春梅，一种类香豆素半花菁荧光染料分子、制备方法及应用，专利号：ZL202411313190.2
主讲课程
本科生课程：《有机化学（1）》、《有机化学（2）》、《有机化学实验（1）》、《有机化学实验（2）》、《药物合成实验》