化学化工学院
王永超
有机化学专业，副教授，博士（硕士生）导师
联系方式：ycwang@ynnu.edu.cn
学术任职及兼职
Organic Letters, Organic Chemistry Frontiers, The Journal of Organic Chemistry, Organic & Biomolecular Chemistry 等期刊审稿人。
主要研究方向
有机合成化学；绿色合成；药物化学研究。
主要招生专业
有机化学；制药工程。
教育与工作经历:
2024年09月至今，云南师范大学化学化工学院，副教授；
2015年09月-2024年08月，云南师范大学职业技术教育学院，讲师、副教授；
2010年09月-2015年07月，云南大学有机化学专业，博士；
2006年09月-2010年07月，云南师范大学应用化学专业，学士。
主持科研项目
1. 云南省科技计划-面上项目（省级），新型3-螺吲哚酮类CDK2/p53-MDM2抑制剂的发现及生物活性评价（编号：202301AT070069），执行时间：2023/06-2026/05；
2. 云南省科技计划-面上项目（省级），靶向CDK2和p53-MDM2的新型蛋白抑制剂的合成及抗肺癌活性研究（编号：ZX20200825005），执行时间：2020/06-2023/05；
3. 云南省科技计划-青年项目（省级），新型多环吡咯类杂环化合物的多样性导向绿色合成及抗肿瘤活性研究（编号：2017FD073），执行时间：2017/10-2020/05。
代表性著作、论文、专利等
1. Zhilai Zhang, Haifeng Sun, Mingshuai Zhang, Siyu Song, Menglin Peng, Weifeng Dai, Yongchao Wang*, Fuchao Yu*. Switchable Skeletal Rearrangement of Hexahydro-4H-indol-4-ones: Divergent Synthesis of Dihydroxy-4H-cyclopenta[b]pyridin-4-ones and 8-Alkenyl Oxepane-2,6-diones. Org. Lett., 2024, 26, 4205-4211.
2. Siyu Song, Menglin Peng, Zhilai Zhang, Huimin Hu, Yuanzheng Wei, Sheng-Jiao Yan*, Yongchao Wang*, and Fuchao Yu*. Divergent Synthesis of 2‑Chromonyl-3-hydrazono-chromones and 2‑Alkoxy-3-hydrazono-chromones through Switchable Annulation Reactions of o‑Hydroxyphenylenaminones with Aryldiazonium Salts. Org. Lett., 2024, 26, 4980-4985.
3. Siyu Song, Zhilai Zhang, Menglin Peng, Xueshan Xia, Shuwei Dong, Yongchao Wang*, Fuchao Yu*. Selective Synthesis of Pyridazine-fused Chromones and 3-Pyridazinyl Chromones through Intermolecular Chromone Annulation of o-Hydroxyphenylenaminones with Aryldiazonium Salts. Org. Chem. Front., 2024, 11, 3906-3912.
4. Yongchao Wang*, Yu Chen, Shengli Duan, Yiyang Cao, Wenjin Sun, Mei Zhang, Delin Zhao, Donghua Hu*, Jianwei Dong*. Diastereoselective Three-component 1,3-Dipolar Cycloaddition to Access Functionalized β-Tetrahydrocarboline- and Tetrahydroisoquinoline-fused Spirooxindoles. Molecules 2024, 29, 1790-1811.
5. Yulin Sun, Zhangmengjie Chai, Donghan Liu, Mingshuai Zhang, Longkun Chen, Zhuoyuan Liu, Yongchao Wang*, Fuchao Yu*. Copper-Catalyzed Oxidative [1+2+1+2] Cascade Cyclization of N,N-Dimethyl Enaminones with Benzylamines: A Facile Access to Functionalized 1,4-Dihydropyridines. Chem. Eur. J., 2023, e202300297.
6. Zhangmengjie Chai, Longkun Chen, Zhuoyuan Liu, Yulin Sun, Donghan Liu, Mingshuai Zhang, Yongchao Wang*, Fuchao Yu*. An Oxidative [3+2+1] Cyclization of Enaminones and N-Alkenyl-2-pyrrolidinone: Access to Polysubstituted 4-Alkylated 1,4-dihydropyridines. Adv. Synth. Catal., 2023, 365, 1217-1223.
7. Siyu Song, Yongchao Wang*, Fuchao Yu*. Construction of 1,4‑Dihydropyridines: The Evolution of C4 Source. Top. Curr. Chem., 2023, 381, 30-62.
8. Longkun Chen, Mingshuai Zhang, Zhuoyuan Liu, Donghan Liu, Yulin Sun, Yongchao Wang*, Fuchao Yu*. Oxidative C(sp3)-N Cleavage Cascade Cyclization of N-Uracil Amidines and Tertiaryamines: Switchable Divergent Synthesis of Functionalized Pyrimidouracils and Dihydropyrimidouracils. Eur. J. Org. Chem., 2023, e202300653.
9. Yongchao Wang*, Lijun Yan, Yuxin Yan, Sujin Li, Hongying Lu, Jia Liu,Jianwei Dong. Dipolarophile-Controlled Regioselective 1,3-Dipolar Cycloaddition: A Switchable Divergent Access to Functionalized N-Fused Pyrrolidinyl Spirooxindoles. Int. J. Mol. Sci., 2023, 24, 3771-3793.
10. Yongchao Wang*, Angel A. Cobo, Annaliese K. Franz*. Recent advances in organocatalytic asymmetric multicomponent cascade reactions for enantioselective synthesis of spirooxindoles. Org. Chem. Front., 2021, 8, 4315-4348.
11. Lijun Yan, Han Xu, Yan Wang, Jianwei Dong*, Yongchao Wang*. Advances in Multicomponent Asymmetric Cascade Synthesis Involving Nitroolefin Catalyzed by Diarylprolinol Derivatives. Chin. J. Org. Chem., 2020, 40, 284-299.
12. Lijun Yan, Yuxin Yan, Xuebing Chen*, Yongchao Wang*. Advances in Multicomponent Asymmetric Cascade Synthesis Involving Hydrogen-Bond-Activated Nitroolefins. Chin. J. Org. Chem., 2020, 40, 856-872.
13. Xuebing Chen*, Shengli Xiong, Zhixu Xie, Yongchao Wang*, Wei Liu*. Three-component one-pot synthesis of highly functionalized bis-indole derivatives. ACS Omega 2019, 4, 11832-11837.
14. Yongchao Wang*, Junliang Wang, Kevin S. Burgess, Jiangwei Zhang, Qiumei Zheng, Yadan Pu, Lijun Yan* and Xuebing Chen*. Green synthesis of new pyrrolidine-fused spirooxindoles via three-component domino reaction in EtOH/H2O. RSC Adv., 2018, 8, 5702-5713.
15. Xuebing Chen, Jiawu Gong, Xudong Zhang, Xiulai Liu, Wei Liu*, Yongchao Wang*. Catalyst-free concise synthesis of multi-functional 3-cyano-4-quinolinone derivatives from cyanoacetylenaminones and DMF-DMA. Tetrahedron 2018, 74, 401-406.
16. Lijun Yan, Junliang Wang, Dan Xu, Kevin S. Burgess, Aifei Zhu, Yanying Rao, Xuebing Chen*, Yongchao Wang*. Chemically sustainable and green one-pot multicomponent synthesis of highly functionalized polycyclic N-fused-pyrrolidine heterocycles. ChemistrySelect 2018, 3, 662-665.
17. Lijun Yan, Yongchao Wang*. Recent advances in green synthesis of 3,3'-Spirooxindoles via isatin–based one–pot multicomponent cascade reactions in aqueous medium. ChemistrySelect 2016, 1, 6948-6960.
18. Dan Xu, Junliang Wang, Lijun Yan, Mingquan Yuan, Xiaotian Xie, Yongchao Wang*. Novel bifunctional L-prolinamide derivatives as highly efficient organocatalysts for asymmetric nitro-Michael reactions. Tetrahedron: Asymmetry 2016, 27, 1121-1132.
主持教学改革项目
1.云南师范大学本科线上线下混合式一流课程建设立项（编号：2020hhkc08），2020年；
2.2021年教育部产学合作协同育人教改项目（编号：202101147024），2021年；
3.2022-2023学年第一学期本科课程等级认定B类；2022年；
4.云南师范大学2023年优势本科专业核心课程建设（B类），2023年；
5.云南师范大学本科课程思政优秀案例，2024年；
6.发表教改论文多篇。
主讲课程
本科生课程《无机化学》、《有机化学》、《药物化学》、《化学与生活》、《食品与药品分析实验》等。