陈业高,男,1965年生,湖北潜江市人,云南师范大学首批特聘教授;云南师范大学化学化工学院副院长,校学术委员会委员,中国科学院新疆理化技术研究所博士生导师;云南师范大学化学化工学院应用化学和有机化学硕士点导师。研究方向为药用植物活性成分提取、分离、纯化、结构鉴定、结构改造和活性研究。
获厅级以上科研成果奖3项,国家专利3项。主编出版著作1本,并在《 Journal of Natural Products 》、《 Phytochemistry 》、《 Helv Chim Acta 》等学术刊物上发表学术论文158篇, 其中SCI 收录 59篇。并多次为《 Spectroscopy Letters 》、《Chinese Journal of Chemistry 》、《Natural Products Research 》、《Biochemical Systematics and Ecology 》、《Journal of the Planar Chromatography》、《高等学校化学学报 》、《武汉植物学研究》、《福建农林大学学报》、《云南大学学报》等杂志评审稿件。
简历:
1984 年毕业于黄石师范学院(现湖北师范学院)化学系,获学士学位
1987 年毕业于云南大学化学系有机合成专业,获硕士学位
1987 年至1995 年在昆明医学院工作,从事天然药物化学研究与教学
1998 年毕业于中国科学院上海药物研究所有机化学专业,获博士学位
1998 年至1999 年在美国弗吉尼亚大学化学系著名有机化学家 S M Hecht 教授课题组做博士后,进行植物和海洋生物中 DNA 作用活性成分的研究
1999 年到云南师范大学化学化工学院工作,从事有机化学、天然药物化学研究与教学,任讲师( 1999.9-2000.8 )、副教授( 2000.9-2001.8 ,破格晋升)、教授( 2001.9 起,破格晋升)。
2004 年 10 月至 2005 年 1 月作为访问教授,应邀赴美国阿拉巴马大学亨茨维尔分校(The University of Alabama at Huntsville)化学系进行药用植物活性成分合作研究。
2009 年 9 月至 2010 年 1 月在美国伊利诺依大学芝加哥分校(University of Illinois at Chicago)药学院药物化学与生药学系做高级研究学者。
获奖及荣誉:
2002 年入选云南师范大学中青年学科带头人
2003 年入选教育部优秀青年教师资助计划和云南省技术创新人才
2004 年入选教育部科技发展中心优秀学者、云南省高等学校教学科研学科带头人
2005年入选教育部新世纪优秀人才、中国科学院 “ 西部之光 ” 人才、云南师范大学首批特聘岗位教授
2006年被评为云南省高校青年学术科技活动标兵,被聘为云南省植物学会第十届理事会常务理事
2007年任云南师范大学化学化工学院副院长,云南师范大学学术委员会委员,获云南省科学技术奖自然科学类二等奖(第一完成人)
2008年被授予“云南省技术创新人才”、 “云南省高等学校教学、科研带头人”称号、 获云南省有突出贡献的专业技术人才三等奖
2010年获中国侨界贡献奖(创新人才)
研究项目:
主持,云南省社会发展基础研究重点项目(2010, 1---2012, 12)
主持,国家自然科学基金(2009, 1---2011, 12)
主持,云南省社会发展基础研究面上项目(2009, 1---2011, 12)
主持完成,科技部国际科技合作重点项目 (2006-2008)
主持完成,教育部新世纪优秀人才支持计划 (2006-2008)
分项目主持完成,国家自然科学基金与云南省地方联合资助项目 (2006-2008)
主持完成,中国科学院 2005 年度 “ 西部之光 ” 人才培养计划 (2006-2007)
主持完成,教育部 “ 优秀青年教师资助计划 ”(2004-2006)
主持完成,云南省科技厅主任基金项目 (2004-2006)
主持完成,云南省科技厅技术创新人才培养项目 (2003-2006)
主持完成,云南省科技厅科学基金项目 (2003-2006)
主持完成,云南省教育厅重点科学基金项目 (2003-2005)
主持完成,国家自然科学基金项目 (2002-2004)
主持完成,云南省科技厅国际合作项目 (2000-2003)
主持完成,教育部留学回国人员基金项目 (2000-2003)
主持完成,云南省教育厅科学基金项目 (2002-2003)
代表性论著:
1. Yang Jian-Hong, Kondratyuk Tamara P., Jermihov KC, Marler Laura E, Qiu Xi, Choi Yongsoo, Cao Hongmei, Yu R, Sturdy Megan, Huang Rong, Liu Ying, Wang Li-Qin, Mesecar Andrew D., Van Breemen Richard B., Pezzuto John M., Fong Harry H. S., Chen Ye-Gao,* and Zhang Hong-Jie, Bioactive compounds from the fern Lepisorus contortus, Journal of natural Products, 2011, 74(2): 129-36.
2. Lian Xiao, Xie Qinghua, Duan Aihong, Chen Yegao*, Phytochemical and pharmacological aspects of Psammosilene tunicoides W. C. Wu et. C. Y. Wu, Asian Journal of Chemistry, 2011, 23(5): 1902-1904.
3. Sun Rong, Song Hong-Chuan, Wang Chun-Ren, Shen Kai-Ze, Xu Yao-Bo, Gao Yan-Xiu, Chen Yegao*, Dong Jin-Yan, Compounds from Kadsura angustifolia with anti-HIV activity, Bioorganic & Medicinal Chemistry Letters, 2011, 21(3): 961–965.
4. Shi Xiaobo, Li Yinjie, Liu Ying, Jiang Jinhe, Wang Liqin, Zhang Yan, Chen Yegao*, A new 9,10-dihydrophenanthropyran dimer and a new natural 9,10-dihydrophenanthropyran from Otochilus porrectus, Biochemical Systematics and Ecology, 2010, 38(4): 842-845
5. Chen Yegao*, Zhang Yan, Liu Ying, Xue Yongmei, Wang Jihua, A new triterpenoid acid from Schisandra henryi, Chemistry of Natural Compounds, 2010, 46(4): 569-571
6. Xie Xiaoyan, Jiang Jinhe, Liu Ying, Min Kang, Xue Yongmei, Jing Bi, Zhang Yan, Chen Yegao*, A New Lycopodine Alkaloid from Phlegmariurus yunnanensis Ching, Helv Chim Acta, 2010, 93(7): 1381-1384.
7. Jiang Jinhe, Liu Ying, Min Kang, Jing Bi, Wang Liqin, Zhang Yan, Chen Yegao*, Two New Lycopodine Alkaloids from Huperzia serrata, Helv Chim Acta, 2010, 93(6): 1187-1191.
8. Yang Jian-Hong, Kondratyuk Tamara P., Marler Laura E, Qiu Xi, Choi Yongsoo, Cao Hongmei, Yu Rui, Sturdy Megan, Pegan Scott, Liu Ying, Wang Li-Qin, Mesecar Andrew D, Breemen Richard B. Van, Pezzuto John M, Fong Harry H.S, Chen Ye-Gao*, Zhang Hong-Jie, Isolation and evaluation of kaempferol glycosides from the fern Neocheiropteris palmatopedata, Phytochemistry, 2010, 71(5-6): 641-647.
9. Chen Yegao*, Tao Yuanyuan, Lian Xiao, Wang Liqin, Zhao Yong, Jiang Jinhe, Zhang Yan, Chemical constituents of Angiopteris esculenta including two new natural lactones, Food Chemistry, 2010, 122(4): 1173-1175
10. Zhan Rui, Min Kang, Zhang Yan, Jiang Jinhe, Liu Ying, Chen Yegao*, Phenolic compounds from Pholidota protracta, Biochemical Systematics and Ecology, 2010, 38(3): 428-430
11. Chen Yegao*, Yang Jian-Hong, Zhang Yan, Liu Ying, A new alloside from Neocheiropteris palmatopedata, Chemistry of Natural Compounds, 2010, 46(2): 173-175
12. Xu Jun-Ju, Qing Chen, Lv Yu-ping, Liu Ya-min, Liu Ying, Chen Yegao*, Cytotoxic rotenoids from Mirabilis jalapa, Chemistry of Natural Compounds, 2010, 46(5): 792-794.
13. Chen Yegao*, Li Jiangtao, Yin Benlin, Liu Ying, Bibenzyls, 9,10-dihydrophenanthrenes, and phenanthraquinone from Dendrobium longicornu, Chemistry of Natural Compounds, 2010, 46(5): 790-791
14. Chen Yegao*, Li Yupeng, Xu Junju, Yu Hong, Zhao Yong, Chemical constituents of Bulbophyllum odoratissimum, Chemistry of Natural Compounds, 2010, 46(5): 787-789
15. Michel Joanna L., Chen Yegao, Zhang Hongjie, Huang Yue, Krunic Aleksej, Orjala Jimmy, Veliz Mario, Soni Kapil K., Soejarto Djaja Doel, Caceres Armando, Perez Alice, Mahady Gail B., Estrogenic and serotonergic butenolides from the leaves of Piper hispidum Swingle (Piperaceae), Journal of Ethnopharmacology, 2010, 129(2): 220-226.
16. Xu Jun-Ju, Yu Hong, Qing Chen, Zhang Yan-Yi, Liu Ying, Chen Ye-Gao*, Two new biphenanthrenes with cytotoxic activity from Bulbophyllum odoratissimum, Fitoterapia, 2009, 80(7): 381-384.
17. Liu Ying, Jiang Jin-He, Zhang Yan, Chen Ye-Gao*, Chemical Constituents of Dendrobium aurantiacum var. denneanum, Chemistry of Natural Compounds, 2009, 45(4): 525-527.
18. Chen Ye-Gao*, Hai Li-na, Liu Ying, Liao Xin-rong, DNA cleavage agents from Schisandra propinqua var. sinensis, African Journal of Biotechnology, 2009, 8 (18): 4650-4652.
19. Li Yu-Peng, Qing Chen, Fang Tian-Tian, Liu Ying, Chen Ye-Gao*, Chemical Constituents of Dendrobium chrysotoxum, Chemistry of Natural Compounds, 2009, 45(3): 414-416
20. Liu Ying, Jiang Jin-He, Yin Ben-Lin, Chen Ye-Gao*, Chemical Constituents of Dendrobium cariniferum, Chemistry of Natural Compounds, 2009, 45(2): 237-238.
21. Li Jiang-Tao, Yin Ben-Lin, Liu Ying, Wang Li-Qin, Chen Ye-Gao*, Mono-aromatic Constituents of Dendrobium longicornu, Chemistry of Natural Compounds, 2009, 45(2): 234-236.
22. Chen Ye-Gao*, Yang Jian-Hong, Zhang Yan, Liu Ying, Chemical Composition of the essential oil of Senecio scandens flowers, Chemistry of Natural Compounds, 2009, 45(1): 114-115.
23. Wang Chun-ren, Sun Rong, Yang Chen-ren-ou, Chen Ye-gao, Song Hong-chuang, Two new lignans from the fruits of Schisandra sphenanthera, Natural product Communications, 2009, 4(11): 1571-1574.
24. Chen Ye-Gao*, Liu Ying, Jiang Jinhe, Zhang Yan, Yin Benlin, Dendronone, a new phenanthrenequinone from Dendrobium cariniferum, Food Chemistry, 2008, 111(1): 11–12
25. Chen Ye-Gao*, Li Yupeng, Qing Chen, Zhang Yan-Li, Wang Li-Qin, Liu Ying, 1,4,5-Trihydroxy-7-methoxy-9H-fluoren-9-one, a new cytotoxic compound from Dendrobium chrysotoxum, Food Chemistry, 2008, 108(3): 973–976.
26. Chen Ye-Gao*, Xu Jun-Ju, Yu Hong, Qing Chen, Zhang Yan-Li, Wang Li-Qin, Liu Ying, Wang Ji-Hua, Cytotoxic phenolics from Bulbophyllum odoratissimum, Food Chemistry, 2008, 107(1): 169–173.
27. Chen Ye-Gao*, Li Jiang-Tao, Wang Li-Qin, Liu Ying, Aromatic compounds from Dendrobium aphyllum, Biochemical Systematics and Ecology, 2008, 36(5-6): 458-460.
28. Chen Ye-Gao*, Zhao Yong, Hu Yuan-Jie, Wang Li-Qin, Ding Zhong-Tao, Liu Ying, Wang Ji-Hua, Isolation of 5-hydroxypyrrolidin-2-one and other constituents from the young fronds of Pteridium aquilinum, Journal of Natural Medicines, 2008, 62(3): 358–359.
29. Chen Ye-Gao, Liu Ying, Setzer William N, Chemical Composition of the Essential Oil of Caragana sinica Flowers, Chemistry of Natural Compounds, 2008, 44(4): 537-538.
30. Setzer William N, Liu Ying, Chen Ye-Gao, Chemical Composition of the Essential Oil of Nothopanax delavayi Leaves, Chemistry of Natural Compounds, 2008, 44(4): 539-540.
31. Wang Li-Qin, Chen Ye-Gao, Xu Jun-Ju, Liu Ying, Li Xiao-Mei, Zhao Yan, Compounds from Viburnum species and their biological activities, Chemistry & Biodiversity, 2008, 5(9): 1879-1899.
32. Li Yu-peng, Zhang Yun-mei, Liu Ying, Chen Ye-Gao*, Chemical Constituents of Dendrobium crystallium, Chemistry of Natural Compounds, 2007, 43(6): 698-699.
33. Chen Ye-Gao*, Xu Jun-Ju, Yu Hong, Qing Chen, Zhang Yan-Li, Liu Ying, Wang Ji-Hua, 3,7-Dihydroxy-2,4,6-trimethoxyphenanthrene, A New Phenanthrene from Bulbophyllum Odoratissimum, Journal of the Korean Chemical Society, 2007, 51(4): 352-355.
34. Dong Jin-Yan, Chen Ye-Gao*, Song Hong-Chuan, He Yan-Ping, Li Lei, Zhong Yong-Ping, Zhu Yan-Hui, Cao Jie, Wang Luo, Zhang Ke-Qin, Hydroxylation of nigranoic acid to 6β-hydroxynigranoic acid by Caryospora carllicarpa YMF1.01026, Chinese Chemilcal Letters, 2007, 18(2): 165-167.
35. Dong Jin-Yan, Chen Ye-Gao, Song Hong-Chuan, Zhu Yan-Hui, Zhou Yong-Ping, Li Lei, He Yan-Ping, Cao Jie , Zhang Ke-Qin, Hydroxylation of the Triterpenoid Nigranoic Acid by the Fungus Gliocladium roseum YMF1.00133, Chemistry & Biodiversity, 2007, 4(2): 112-117
36. Chen Ye-Gao*, Song Xiao-Ping, Hai Li-Na, A Fang, Bi Yun-Mei, Liao Xin-Rong, Triterpenoid Acids from Kadsura ananosma, Polish J Chem, 2006, 80 (10): 1677-1682
37. Chen Ye-Gao*, Song Xiao-Ping, Hai Li-Na, Lv Yu-Ping, A Fang, Halaweish F, Liao Xin-Rong, Compounds with DNA cleaving activity from Kadsura ananosma, Pharmazie, 2006, 61(10): 891-892.
38. Yu Li-Li, Han Chang-Ri, Huang Rong, Lv Yu-Ping, Gui Shi-Hong, Chen Ye-Gao*, A new iridoid tetraester from Valeriana jatamansi, Pharmazie, 2006, 61(5): 486-488
39. Bi Yun-Mei, Bi Xue-Bin, Zhao Qin-Rong, A Fang, Chen Ye-Gao, Dihydroisocoumarins from the Fungus, Cephalosporium sp. AL031, Polish J Chem, 2006, 80 (3): 387–396
40. Bi Yun-Mei, Bi Xue-Bin, Zhao Qin-Rong, A Fang, Chen Ye-Gao, A new pyrone derivative from Fungus Cephalosporium sp. AL031, Chin Chem Lett, 2006, 17 (3): 344–346
41. Chen Ye-Gao*, Yu Li-Li, Huang Rong, Liu Jia-Chuan, Lv Yu-Ping, Zhao Yong, 3’’-Hydroxyamentoflavone and Its 7-O-methyl Ether, Two New Biflavonoids from Aristolochia contorta, Arch Pharm Res, 2005, 28(11):1233-1235.
42. Chen Ye-Gao*, Wu Zheng-Cai, Gui Shi-Hong, Lv Yu-Ping, Liao Xin-Rong, Halaweish Fathi, Lignans from Schisandra hernyi with DNA cleaving activity and cytotoxic effect on leukemia and Hela cells in vitro, Fitoterapia, 2005, 76(3-4): 370-373
43. Chen Ye-Gao*, Yu Li-Li, Huang Rong, Lv Yu-Ping, Gui Shi-Hong, 11-Methoxyviburtinal, A New Iridoid from Valeriana jatamansi, Arch Pharm Res, 2005, 28(10): 1161-1163.
44. Yu Li-Li, Huang Rong, Han Chang-Ri, Lv Yu-Ping, Zhao Yong, Chen Ye-Gao*, New Iridoid Triesters from Valeriana jatamansi, Helvetica Chimica Acta, 2005, 88(5): 1059-1062.
45. Yu Lili, Huang Rong, Lv Yuping, Zhao Yong, Chen Yegao*, A new biflavonoid from Aristolochia contorta, Pharmazie, 2005, 60(10): 389-391.
46. Yu Li-Li, Chen Ye-Gao *, Liu Jia-Chuan, Lu Yu-Ping and Gui Shi-Hong, Chalcones from the seeds of Psoralea corylifolia, Polish J Chem, 2005, 79 (7): 1173- 1178
47. Chen Ye-Gao, Hai Li-Na, Liao Xin-Rong, Qin Guo-Wei, Xie Yu-Yuan, Halaweish Fathi, Ananosic acids B and C, Two New 18 (1312) Abeo Lanostane Triterpenoids from Kadsura anaosma, Journal of Natural Products, 2004, 67(5): 875-877
48. Chen Ye-Gao, Wu Zheng-Cai, Lv Yu-Ping, Gui Shi-Hong, Wen Jin, Liao Xin-Rong, Yuan Li-Ming, Halaweish Fathi, Triterpenoids from Schisandra henryi with Cytotoxic Effect on Leukemia and Hela Cells In Vitro, Arch Pharm Res, 2003, 26 (11): 912-916
49. Chen Ye-Gao, Xie Yu-Yuan, Cheng Kin-Fai, Cheung Kung-Kai, Qin, Guo-Wei, Compounds from Kadsura ananosma, Phytochemistry, 2001, 58(8): 1277-1280
50. Chen Ye-Gao, Qin Guo-Wei, Cao Lin, Xie Yu-Yuan, Triterpenoid acids with cytotoxic effect on rat luteal cells and human decidual cells in vitro from Schisandra propinqua, Fitoterapia, 2001, 72(4): 434-436
51. Chen Ye-Gao, Qin Guo-Wei, Xie Yu-Yuan, A novel triterpenoid lactone, schiprolactone A, from Schisandra propinqua (Wall.) Hook. f. et Thoms, Chinese J. of Chemistry, 2001, 19(3): 304-307
52. Yuan Li-ming, Ai Ping, Chen Xue-xin, Zi Ming, Wu Ping, Li Zheng-yu, Chen Ye-Gao, Versative two-phase solvent system for flavonoid prefractionation by high speed countercurrent chromatography, J. Liq. Chroma. & Rel. Technol., 2002, 25(6): 889-897
53. Qin Guo-Wei, Hamed Arafa I., El-Emary Nasr A., Chen Ye-Gao, Wang Li-Quang, Cheung Kung-Kai, Cheng Kin-Fai, A New Trinortriterpenoid from Cleome chrysantha, Planta Medica, 2000, 66: 191
54. Chen Ye-Gao, Wang Ping, Lin Zhong-Wen, Sun Hang-Dong, Qin Guo-Wei, Xie Yu-Yuan, Dibenzocyclooctadiene Lignans from Kadsura angustifolia, Phytochemistry, 1998, 48(6):1059
55. Chen Ye-Gao, Qin Guo-Wei, Xie Yu-Yuan, Cheng Kin-Fai, Lin Zhong-Wen, Sun Hang-Dong, Kang Young-Hwa, Han Byung-Hoon, Lignans from Kadsura angustifolia, Journal of Asian Natural Products Research, 1998, 1(2): 125
56. Chen Ye-Gao, Hamed Arafa I. El-Emary Nasr A., Qin Guo-Wei, Cheung Kung-Kai, Cheng Kin-Fai, A New Trinortriterpenoid from Cleome chrysantha, Chinese Chemical Letters, 1998, 9(12):1093
57. 陈业高主编,植物化学成分,北京:化学工业出版社, 2004 年 4 月
教学:
1. 负责的云南师范大学化学实验教学中心被评为云南省实验教学中心(2010年)
2. 负责的《植物化学》课程被评为云南省精品课程(2010年)
3. 主编的《植物化学成分》获云南省优秀教材(2009年)